Aerosol bronchodilator administration in ventilator circuits

New bronchodilator aerosol preparations.

Correspondence MBIRrNAL 421 hysteria or to altered xnedical perception in the community. Their erroneous conclusions about this illness may impair future investigations of similar outbreaks. It is apparent that the authors failed to do their homework, and demonstrated a surprising lack of information about the principles of epidemiology and of psychiatry. Had they reviewed the literature on the...

Bronchodilator Therapy in Mechanically Ventilated Patients

Introduction Basic Concepts of Aerosol Therapy Inertial Impaction Gravitational Sedimentation Diffusion The Nebulizer The Metered Dose Inhaler Differences during Mechanical Ventilation The Ventilator-Patient Interface Breath Configurations The Airway The Environment The Assessment Evaluation of Lower Respiratory Tract Aerosol Delivery with Bench Models of Mechanical Ventilation Aerosol-Generati...

Inhaled bronchodilator administration during mechanical ventilation.

Inhaled bronchodilators are routinely administered to mechanically ventilated patients to relieve dyspnea and reverse bronchoconstriction. A lower percentage of the nominal dose reaches the lower respiratory tract in a mechanically ventilated patient than in a nonintubated subject, but attention to device selection, administration technique, dosing, and patient-ventilator interface can increase...

Inhalation therapy with metered-dose inhalers and dry powder inhalers in mechanically ventilated patients.

Pressurized metered-dose inhalers (pMDIs) are commonly employed for administering bronchodilator aerosols to mechanically ventilated patients. Although it is feasible to employ dry powder inhalers in ventilator circuits, the presence of humidity in the ventilator circuit could reduce their efficiency. A complex array of factors influence drug delivery from pMDIs during mechanical ventilation, a...

Clinical assessment of bronchodilator drugs delivered by aerosol.